Why the study?
Because the exact pathophysiology of ACAOS is not well-understood, there is a lack of evidence-based guidelines addressing diagnostic work-up, downstream testing, sports counseling, and therapeutic options.
Population
Patients with anomalous coronary arteries originating from the opposite sinus of Valsalva (ACAOS)
Design
Review
Authors
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ACAOS diagnostic uncertainties persist; leaves open evidence-based risk stratification and management pending prospective data.
This review outlines the pathophysiological mechanisms of ischemia in ACAOS and highlights the current gaps in evidence regarding optimal diagnostic work-up and clinical management.
Bigler et al. (2021) studied this question.
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