Blockade of the transcriptional coactivator p300 prevents glucose-induced cardiomyocyte hypertrophy, highlighting a potential epigenetic target for diabetic cardiomyopathy.
No takes yet. Share an insight, caveat, or question.
p300 blockade merits investigation as an epigenetic target in diabetic cardiomyopathy; hypothesis-generating in animal models only.
Feng et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: