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April 15, 2020SHILAP Revista de lepidopterología187 citationsOpen Access

Multiple links between 5-methylcytosine content of mRNA and translation

USUlrike SchümannAustralian National UniversityHZHena ZhangJiangsu Normal UniversityTSTennille SibbrittChildren's Medical Research Institute

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Abstract

Our findings emphasise the major role of NSUN2 in placing the m5C mark transcriptome-wide. We further present evidence that substantiates a functional interdependence of cytosine methylation level with mRNA translation. Additionally, we identify several compelling candidate sites for future mechanistic analysis.

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Schümann et al. (2020) studied this question.

synapsesocial.com/papers/69d8911e52654bb436d194fchttps://doi.org/10.1186/s12915-020-00769-5
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