Dehydrative formation and biological evaluation of allylic sulfonamides from allylic alcohols using recyclable silica-supported acid catalysts

Key Points

• The aim is to develop a recyclable catalytic system for the synthesis of allylic sulfonamides from allylic alcohols and assess their biological activity.
• Developed a transition-metal-free catalytic system.
• Used silica-supported acid catalysts for the reaction.
• Conducted reactions under mild conditions.
• Successfully prepared allylic sulfonamides from allylic alcohols.
• Novel compounds exhibited notable biological properties.