Case-control study identifies serum protein alterations and potential therapies in cats with oral inflammation.
FCGS extends beyond localized oral inflammation to involve measurable systemic immune dysregulation. Hyperglobulinemia, combined with oromucosal inflammation, should prompt diagnostic consideration of FCGS in cats. The coordinated activation of IL-8, IL-4, IFN-γ, and IL-6 identifies potential therapeutic targets for immunomodulatory intervention in refractory cases.
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Tetlow et al. (2026) studied this question.
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