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June 21, 2001

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Early Gastric Cancer in Young, Asymptomatic Carriers of Germ-Line E-Cadherin Mutations

David G. HuntsmanThe Wistar Institute FCFátima CarneiroUniversidade do Porto FLFrank R. LewisManchester University NHS Foundation Trust

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Resumen

We recommend genetic counseling and consideration of prophylactic gastrectomy in young, asymptomatic carriers of germ-line truncating CDH1 mutations who belong to families with highly penetrant hereditary diffuse gastric cancer.

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Early Gastric Cancer in Young, Asymptomatic Carriers of Germ-Line E-Cadherin Mutations | Synapse

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Huntsman et al. (Thu,) studied this question.

synapsesocial.com/papers/69d89453d2f7327e70ae37ca https://doi.org/https://doi.org/10.1056/nejm200106213442504

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