⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

April 6, 2026Current Neurovascular Research

Molecular Morse Code: cAMP and cGMP Signaling in Health and Pathogenesis

Ahsas Goyal Sushma Singh Neetu Agrawal Nandini Dubey Aanchal Verma

View Full Paper

Ask AI

Bookmark

Share

Key Points

The paper aims to explore the roles of cAMP and cGMP in physiological processes and their implications in diseases.
Electronic searches conducted using PubMed, Scopus, Web of Science, and Google Scholar.
Search terms included 'cAMP', 'cGMP', or 'cyclic nucleotide' with terms like 'neuroprotective', 'cardioprotective', and 'cancer'.
Relevant studies were reviewed to assess the roles of cyclic nucleotides.
Cyclic nucleotide phosphodiesterases (PDEs) modulate cAMP and cGMP signaling pathways.
Dysregulation of cyclic nucleotide signaling is linked to cardiovascular disorders, neurological diseases, cancers, and bone conditions.
Targeting PDEs could offer new therapeutic strategies for these diseases.

Implication

Reviews the roles of cyclic nucleotides in cellular signaling, highlighting implications for therapy in various diseases.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Goyal et al. (2026) studied this question.

synapsesocial.com/papers/69d8948f6c1944d70ce05724 https://doi.org/10.2174/0115672026446100260327052417

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Cyclic nucleotide regulation of cardiac sympatho‐vagal responsivenessreview · 2016 · 18 citations
2Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase.review · 2004 · 115 citations
3cGMP Signaling in Cardiovascular Diseases: Linking Genotype and Phenotypereview · 2020 · 22 citations
4Phosphodiesterases and Cyclic Nucleotide Signaling in Endocrine Cellsreview · 2000 · 175 citations
5Cyclic nucleotide phosphodiesterase-mediated integration of cGMP and cAMP signaling in cells of the cardiovascular systemreview · 2005 · 39 citations