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April 10, 2026The International Journal of Gastroenterology and Hepatology Diseases

Unraveling the Complex Pathogenesis, Diagnosis, and TherapeuticInterventions of Inflammatory Bowel Disease

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Authors

MSMohammad Akbar SiddiquiNANavneet AgrawalSGSakshi Gupta

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Overview

This review explores IBD's causes, diagnostic techniques, and treatments, highlighting future research needs.

Key Points

  • To provide a comprehensive overview of the mechanisms, diagnosis, and treatment options for Inflammatory Bowel Disease (IBD).
  • Review of genetic studies identifying susceptibility loci like NOD2 and ATG16L1.
  • Analysis of dysbiosis in gut microbiota and its impact on immune regulation.
  • Discussion of environmental factors influencing IBD onset and progression.
  • Overview of diagnostic approaches including serological, stool-based, and imaging methods.
  • Examination of therapeutic strategies, including medications and microbiome-based interventions.
  • Identification of immune cell activation patterns contributing to inflammation in IBD.
  • Recognition of the role of environmental factors like diet and stress in disease exacerbation.
  • Overview of current therapeutic options aimed at inducing remission and maintaining mucosal healing.

Cite This Study

Siddiqui et al. (2026) studied this question.

synapsesocial.com/papers/69d894ad6c1944d70ce05905https://doi.org/10.2174/0126662906449437260324041201
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