What question did this study set out to answer?

The research aims to evaluate the feasibility of vNOTES hysterectomy with SLN mapping and assess postoperative lymphedema incidence.

April 10, 2026Current OncologyOpen Access

Minimizing Lymphatic Morbidity: Incidence of Lower Extremity Lymphedema After vNOTES-Assisted Sentinel Node Mapping in Endometrial Cancer

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Retrospective cohort study evaluates lower extremity lymphedema post-vNOTES-assisted SLN mapping in endometrial cancer, suggesting less morbidity.

The research aims to evaluate the feasibility of vNOTES hysterectomy with SLN mapping and assess postoperative lymphedema incidence.
Conducted a retrospective cohort study with 113 patients
Utilized vNOTES-assisted hysterectomy with bilateral salpingo-oophorectomy and SLN mapping
Lymphedema assessed using the Gynecologic Cancer Lymphedema Questionnaire at 6 and 12 months post-surgery
Performed descriptive statistical analyses on clinical characteristics and lymphedema symptoms.
Successful SLN mapping in 102 of 113 patients, achieving a detection rate of 90.3%
Reported limb swelling in 4.1% of patients
Only 1.0% of patients met criteria for mild lymphedema
No clinical signs of inguinal lymphedema were detected.

Kurtuluş et al. (2026) studied this question.

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Retrospective cohort study evaluates lower extremity lymphedema post-vNOTES-assisted SLN mapping in endometrial cancer, suggesting less morbidity.