Why the study?
Does 18F-FAPI PET/CT imaging detect early fibro-inflammatory activity predictive of coronary restenosis?
Does 18F-FAPI PET/CT imaging detect early fibro-inflammatory activity predictive of coronary restenosis?
18F-FAPI PET/CT imaging may serve as a novel non-invasive tool to detect early fibro-inflammatory activity predictive of coronary in-stent restenosis.
Should not yet change post-stent surveillance; leaves open value of 18F-FAPI PET/CT to predict in-stent restenosis.
A 49-year-old woman with chronic total occlusion of the proximal left anterior descending (LAD) artery underwent a baseline 18F-FAPI PET/CT, and showed no abnormal uptake in the coronary artery. New focal 18F-FAPI activity appeared at the LAD stent ostium at 6 months and progressed by 1 year, preceding angiographically confirmed in-stent restenosis. This case demonstrates that 18F-FAPI imaging may detect early fibro-inflammatory activity predictive of restenosis.
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Xi et al. (2026) studied this question.
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