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April 10, 2026TrAC Trends in Analytical ChemistryOpen Access

From Paper to Polymers: Substrate Engineering in Point-of-Care Colorimetric Sensors for Ionic Species Detection

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Authors

JSJonatas de Oliveira S. SilvaJSJosé dos SantosRSRodolfo M.M. Santana

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Overview

This review examines substrate engineering to enhance ionic species detection in colorimetric sensors, highlighting key advancements and challenges.

Key Points

  • The review aims to explore how substrate engineering can optimize colorimetric sensors for detecting ionic species.
  • Review of recent advances in solid-substrate colorimetric sensors.
  • Analysis of various colorimetric agents, including molecular dyes and nanostructures.
  • Discussion of surface modification and immobilization strategies.
  • Evaluation of digital image analysis for improving sensing performance.
  • Identification of challenges related to reproducibility and field conditions.
  • Substrate engineering significantly improves colorimetric sensor performance.
  • The use of metal nanoparticles and nanozymes enhances detection mechanisms.
  • Engineered polymer substrates offer better reliability compared to traditional paper-based materials.
  • Effective co-design of substrates and chromogenic systems is crucial for robust sensor deployment.
  • Key gaps in validation and sustainability need addressing for real-world applications.

Cite This Study

Silva et al. (2026) studied this question.

synapsesocial.com/papers/69d894ec6c1944d70ce05dd9https://doi.org/10.1016/j.trac.2026.118841
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