What question did this study set out to answer?

Investigate an outbreak of highly pathogenic avian influenza A(H5N1) in an intensive mink farming facility.

January 19, 2023EurosurveillanceOpen Access

Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022

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Investigate an outbreak of highly pathogenic avian influenza A(H5N1) in an intensive mink farming facility.
Investigated an outbreak occurring in October 2022 at a single intensive farm housing more than 50,000 minks in northwest Spain.
Conducted virological and genetic characterization of the isolated virus strains.
Identified the circulating strain as highly pathogenic avian influenza A(H5N1) belonging to clade 2.3.4.4b.
Detected an uncommon T271A mutation in the viral PB2 gene associated with mammalian adaptation.
Found epidemiological and virological indications of onward transmission between minks within the facility.

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Implication

Outbreak investigation uncovers avian influenza A(H5N1) with mammal-adapting PB2 mutations in farmed minks, highlighting potential mammalian transmission risks.

Cite This Study

Agüero et al. (2023) studied this question.

synapsesocial.com/papers/69d8956cd2f7327e70ae3807 https://doi.org/10.2807/1560-7917.es.2023.28.3.2300001

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Implication

Outbreak investigation uncovers avian influenza A(H5N1) with mammal-adapting PB2 mutations in farmed minks, highlighting potential mammalian transmission risks.

Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022

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Implication

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Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022

Key Points

Discussion

Implication

Cite This Study

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