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Research Paper | Synapse

April 10, 2026International Endodontic Journal0 citations

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Foxq1‐Wnt5a Axis Activation in Dental Papilla Stem Cells Promotes Odontogenesis on Acellular Matrix: A Laboratory Investigation

JKJingjing KeStomatology Hospital MZM ZhangSun Yat-sen University LKLixian KongStomatology Hospital

Key Points

This study aims to explore how the Foxq1-Wnt5a signaling pathway influences odontogenesis in dental papilla stem cells.
Laboratory investigation of Foxq1-Wnt5a axis activation.
Utilization of acellular dentine scaffolds for testing.
Analysis of tubular dentine regeneration.
Activation of Foxq1-Wnt5a significantly enhanced odontogenesis.
Successful tubular dentine regeneration observed on acellular matrix.
Findings suggest a synergistic effect between signaling pathways and scaffolds.

Abstract

The activation of the Foxq1-Wnt5a signalling axis synergizes with acellular dentine scaffolds to promote tubular dentine regeneration.

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Cite This Study

Ke et al. (Wed,) studied this question.

synapsesocial.com/papers/69d895796c1944d70ce066a8 https://doi.org/https://doi.org/10.1111/iej.70160