What question did this study set out to answer?

To evaluate the safety and efficacy of clozapine in a patient with treatment-resistant schizophrenia and epilepsy.

Clozapine for treatment‐resistant schizophrenia with epilepsy: A case report

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Case report finds effective clozapine use in treating schizophrenia and epilepsy, suggesting safety in combined conditions.

To evaluate the safety and efficacy of clozapine in a patient with treatment-resistant schizophrenia and epilepsy.
Case presentation of a 36-year-old male with TRS and focal epilepsy.
Clozapine initiated at 6.25 mg, titrated to 250 mg over 3 months.
Monitoring included plasma concentration assessment and long-term video electroencephalography.
Psychotic symptoms improved significantly during treatment.
No increase in seizure frequency or severity was observed.
Mild side effects like drowsiness and drooling were manageable.

Horinouchi et al. (2026) studied this question.

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