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April 10, 2026Transboundary and Emerging DiseasesOpen Access

Antimicrobial Resistance, Virulence, and Genomic Characteristics of Klebsiella pneumoniae Isolated From Four Host Sources in Northeast China

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Authors

QXQiu XuCFChao FanYLYaowei Liu

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Overview

Examines antimicrobial resistance and virulence in Klebsiella pneumoniae from multiple hosts, highlighting cross-species transmission concerns.

Key Points

  • The study aims to analyze the genomic characteristics and antimicrobial resistance profiles of Klebsiella pneumoniae from different host sources in Northeast China.
  • Whole-genome sequencing of 112 Klebsiella pneumoniae isolates from four host sources
  • Characterization of phylogenetic relationships among isolates
  • Antimicrobial susceptibility testing to assess resistance profiles
  • Virulence gene screening for key markers of hypervirulence
  • Identified 53 distinct sequence types and 38 K-locus types among isolates
  • 78.6% of isolates classified as multidrug resistant
  • Higher resistance rates observed in human and pig-derived isolates compared to those from chickens and dairy cows
  • 34 isolates carried virulence genes associated with hypervirulence, falling into two distinct phylogenetic lineages

Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/69d895a86c1944d70ce06c1ahttps://doi.org/10.1155/tbed/1252580
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Also Consider

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  1. 1Epidemiological, Virulence, and Antibiotic Resistance Analysis of Klebsiella pneumoniae, a Major Source of Threat to Livestock and Poultry in Some Regions of Xinjiang, China2024 · 13 citations
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  3. 3Molecular Characteristics of <i>Klebsiella pneumoniae</i> Isolated from Pigs Originating in Xinxiang, Henan Province2026
  4. 4Decoding Klebsiella pneumoniae in poultry chain: unveiling genetic landscape, antibiotic resistance, and biocide tolerance in non-clinical reservoirs2024 · 12 citations
  5. 5Genomic and phenotypic insights into antibiotic resistance and virulence of <i>Klebsiella pneumoniae</i> from the environment in Southern Taiwan2025