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This research investigates the factors leading to septic shock and 90-day mortality following intra-abdominal infections in postoperative patients.

April 10, 2026

Determinants of Septic Shock and 90-Day Mortality after Postoperative Healthcare-Associated Intra-Abdominal Infection: The SEPSI-POP study, a Multicentre Retrospective Study.

Key Points

This research investigates the factors leading to septic shock and 90-day mortality following intra-abdominal infections in postoperative patients.
Multicentre retrospective study design
Analysis of patient data with focuses on risk factors
Examination of fungal colonization and frailty as shared risks
Assessment of age, organ failure, and source control effectiveness for mortality
Fungal colonization and frailty identified as common risk factors for septic shock
Age and organ failure were significant predictors of 90-day mortality
Inadequate source control correlated with increased mortality rates

Abstract

Determinants of septic shock and 90-day mortality partly overlap but differ in therapeutic implications. Fungal colonization and patient frailty emerged as shared risk factors, while mortality was influenced by age, organ failure, and inadequate source control. Early identification of high-risk profiles and timely, targeted interventions may improve outcomes in postoperative HC-IAI.

Determinants of Septic Shock and 90-Day Mortality after Postoperative Healthcare-Associated Intra-Abdominal Infection: The SEPSI-POP study, a Multicentre Retrospective Study.

Key Points

Abstract

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