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April 10, 2026Journal of Burn Care & ResearchOpen Access

Case Study. Achieving Successful Closure of Necrotizing Soft Tissue Infection Wound with Autograft and Bioresorbable Antimicrobial Matrix (A Case Study)

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Authors

CFCarmen Flores

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Overview

Case study demonstrates successful wound closure in a septic patient using a bioresorbable antimicrobial matrix, indicating potential for enhanced healing.

Key Points

  • This report aims to describe the successful closure of a wound from a necrotizing soft tissue infection using innovative healing methods.
  • Patient with extensive necrotizing soft tissue infection underwent aggressive wound excision.
  • Negative pressure wound therapy and an electrospun fiber matrix were applied for optimal healing.
  • Split-thickness skin grafting and epidermal autograft spray were performed after wound bed preparation.
  • A bioresorbable antimicrobial matrix was administered over the autografts prior to secondary dressings.
  • By post-operative day four, the graft was unoccluded and 90% epithelialized.
  • Complete wound closure was achieved by post-operative day five.
  • Donor site healing was observed by day seven with no recurrent infection beyond initial presentation.
  • Functional outcomes were excellent, with no contracture noted.

Cite This Study

Carmen Flores (2026) studied this question.

synapsesocial.com/papers/69d895d86c1944d70ce06e7bhttps://doi.org/10.1093/jbcr/irag033.190
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  3. 31014. Case Study. Skin Cell Suspension (SCSA) for Complex Necrotizing Soft Tissue Infections: A Case Series2026
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