What question did this study set out to answer?

This study aims to compare the prevalence and antibiotic susceptibility of community-acquired and hospital-acquired MRSA infections.

April 10, 20260 citationsOpen Access

A comparison of Hospital and Community acquired Methicillin resistant Staphylococcus aureus infections in a tertiary care hospital

SOS Oommen RGRony George NKNisha Kurian

Key Points

This study aims to compare the prevalence and antibiotic susceptibility of community-acquired and hospital-acquired MRSA infections.
Included 30 non-duplicate MRSA isolates from various specimens over three months
Analyzed antibiotic susceptibility patterns
Identified important risk factors for MRSA infection
Used Fisher's exact test to assess statistical significance
16.67% of isolates were community-acquired MRSA (CA-MRSA) compared to 83.33% hospital-acquired (HA-MRSA)
CA-MRSA isolates showed distinct susceptibility patterns from HA-MRSA
Awareness of community presence of MRSA is crucial due to treatment implications

Abstract

Objectives: Traditionally, MRSA infections occurred exclusively in hospitals namely Hospital-acquired Methicillin-resistant Staphylococcus aureus (HA-MRSA).Recently however, community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged in young individuals without risk factors for MRSA acquisition.Prevalence of CA-MRSA and its susceptibility to antibiotics have shown geographic variability.Methods: This study aims to provide regionally specific information on the proportion of CA-MRSA cases.Thirty non-duplicate MRSA isolated from different specimens for a period of three months were included in the study.Antibiotic susceptibilities and the important risk factors for infection were studied.The Fisher's exact test was done to determine the statistical significance.Results: 16.67% of our isolates were community-acquired and 83.33% were hospital-acquired.CA-MRSA isolates were distinct from HA-MRSA by their susceptibility patterns and risk factors.Conclusions: Beta-lactam antibiotics are usually the first line antibiotics used to treat a staphylococcal infection.Awareness about the existence of MRSA in the community is a must as the commonly used beta lactams have no role in treatment of these staphylococcal infections.

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