What question did this study set out to answer?

The study aims to assess the efficacy of corticosteroids in burn patients experiencing suspected corticosteroid insufficiency during critical illness.

April 10, 2026Journal of Burn Care & ResearchOpen Access

Evaluation of Hydrocortisone Use in Suspected Critical Illness-related Corticosteroid Insufficiency in Hypotensive Burn Patients

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The study aims to assess the efficacy of corticosteroids in burn patients experiencing suspected corticosteroid insufficiency during critical illness.
Reviewed cases of burn patients requiring vasopressors from January 2015 to December 2025.
Defined critical illness-related corticosteroid insufficiency as treatment with corticosteroids.
Analyzed demographics, burn data, hospital course, and treatment outcomes using statistical tests.
Among 87 patients, 47 received corticosteroids for CIRCI and 40 did not.
CIRCI patients had an average cortisol level of 13.7 mcg/dL compared to 20.2 mcg/dL in non-CIRCI.
CIRCI patients had longer hospital stays (52.24 vs 28.22 days) and more infections (66% vs 34%).
Older age and greater resuscitation fluids were linked to CIRCI diagnosis, while corticosteroid use correlated with increased infections.

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Implication

This evaluation finds associations between corticosteroid treatment and outcomes in hypotensive burn patients, suggesting further studies are needed.

Cite This Study

Dean et al. (2026) studied this question.

synapsesocial.com/papers/69d8967d6c1944d70ce07f44 https://doi.org/10.1093/jbcr/irag033.296

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Implication

This evaluation finds associations between corticosteroid treatment and outcomes in hypotensive burn patients, suggesting further studies are needed.

Evaluation of Hydrocortisone Use in Suspected Critical Illness-related Corticosteroid Insufficiency in Hypotensive Burn Patients

Key Points

Discussion

Implication

Cite This Study

Evaluation of Hydrocortisone Use in Suspected Critical Illness-related Corticosteroid Insufficiency in Hypotensive Burn Patients

Key Points

Discussion

Implication

Cite This Study

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