What question did this study set out to answer?

This research aims to explore the regioselective acylation of the phenanthrene skeleton, focusing on C3- and C10-acylation.

C3- vs C10-Acylation of 9-Methoxyphenanthrene Controlled by Non-Covalent Interactions

View Full Paper

Ask AI

Bookmark

This research aims to explore the regioselective acylation of the phenanthrene skeleton, focusing on C3- and C10-acylation.
Developed a regiodivergent acylation approach for phenanthrene skeleton.
Synthesized C3- and C10-acylated products and assessed yields.
Utilized DFT calculations to examine non-covalent interactions influencing regioselectivity.
Obtained C3- and C10-acylation products with good to high yields.
DFT calculations indicated that regioselectivity was influenced by Coulomb repulsion, π-π stacking, hydrogen bonding, and steric effects.

No takes yet. Share an insight, caveat, or question.

Acylation demonstrates regioselectivity in phenanthrene derivatives, suggesting insights into molecular interactions.

Yao et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark