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July 15, 1994Science

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

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Authors

YCYunje ChoPohang University of Science and TechnologySGSvetlana S. GorinaRussian Academy of SciencesPJPhilip D. JeffreyPrinceton University

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Cho et al. (1994) studied this question.

synapsesocial.com/papers/69d899c618b0ca7f91d18665https://doi.org/10.1126/science.8023157
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression1992 · 344 citations
  2. 2Improved methods for building protein models in electron density maps and the location of errors in these models1991 · 12,688 citations
  3. 3WAF1, a potential mediator of p53 tumor suppression1993 · 8,421 citations
  4. 4Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication1991 · 381 citations
  5. 5A transcriptionally active DNA-binding site for human p53 protein complexes.1992 · 722 citations