Does exercise-based cardiac rehabilitation reduce mortality and cardiovascular events in patients with coronary heart disease?
Exercise-based cardiac rehabilitation reduces cardiovascular mortality and hospitalizations in lower-risk patients following MI or revascularization, supporting its role in secondary prevention.
This updated Cochrane review supports the conclusions of the previous version of this review that, compared with no exercise control, exercise-based CR reduces the risk of cardiovascular mortality but not total mortality. We saw a significant reduction in the risk of hospitalisation with CR but not in the risk of MI or revascularisation. We identified further evidence supporting improved HRQL with exercise-based CR. More recent trials were more likely to be well reported and include older and female patients. However, the population studied in this review still consists predominantly of lower risk individuals following MI or revascularisation. Further well conducted RCTs are needed to assess the impact of exercise-based CR in higher risk CHD groups and also those presenting with stable angina. These trials should include validated HRQL outcome measures, explicitly report clinical event outcomes including mortality and hospital admissions, and assess costs and cost-effectiveness.
Anderson et al. (Tue,) studied this question.
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