August 1, 1981Circulation
Angiographic prevalence of high-risk coronary artery disease in patient subsets (CASS).
Why the study?
What is the angiographic prevalence of high-risk coronary artery disease in patients presenting with different types of chest pain?
Population
8,157 patients with definite angina, probable angina, and nonspecific chest pain out of an initial 20,391…
Design
Cross-sectional
Authors
Discussion
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Implication
May inform noninvasive testing decisions by chest pain category and sex; hypothesis-generating for sex-specific pretest probability models.
Structured PICO
What is the angiographic prevalence of high-risk coronary artery disease in patients presenting with different types of chest pain?
P
Population
8,157 patients with definite angina, probable angina, and nonspecific chest pain (excluding unstable angina or myocardial infarction) out of an initial 20,391 patients who underwent angiography in the Coronary Artery Surgery Study from 1975-1979.
I
Intervention
Coronary angiography
O
Outcome
Prevalence of coronary artery stenoses ≥70% or left main stenosis ≥50%surrogate
High-risk coronary disease is common in middle-aged patients with definite angina and older patients with probable angina, but rare in patients with nonspecific chest pain, which can guide the appropriate use of diagnostic testing.
Cite This Study
Chaitman et al. (1981) studied this question.