What question did this study set out to answer?

To establish updated, internationally validated classification criteria for systemic lupus erythematosus with optimized sensitivity and specificity for clinical studies.

August 6, 2019Arthritis & RheumatologyOpen Access

2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus

View Full Paper

Ask AI

Bookmark

Authors

MAMartin AringerDresden International University KCKaren H. CostenbaderBoston University DDDavid DaikhOregon Health & Science University

Discussion

Member takes

Implication

International consensus study demonstrates high sensitivity and specificity of new classification criteria in systemic lupus erythematosus, indicating a refined foundation for research.

Key Points

To establish updated, internationally validated classification criteria for systemic lupus erythematosus with optimized sensitivity and specificity for clinical studies.
Employed an international, multidisciplinary consensus methodology to develop and refine disease classification standards.
Established antinuclear antibody (ANA) positivity as an obligatory initial entry criterion.
Organized clinical and immunological manifestations into hierarchically clustered and weighted criteria domains.
Demonstrated excellent sensitivity and specificity for classifying systemic lupus erythematosus.
Implemented a weighted scoring framework that accurately reflects current clinical understanding of disease manifestations.
Established a standardized foundation to improve cohort definition in future clinical trials and observational research.

Cite This Study

Aringer et al. (2019) studied this question.

synapsesocial.com/papers/69d8c424d2f7327e70ae4331 https://doi.org/10.1002/art.40930

View Full Paper

Ask AI

Bookmark

Implication

International consensus study demonstrates high sensitivity and specificity of new classification criteria in systemic lupus erythematosus, indicating a refined foundation for research.

2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus

Discussion

Member takes

Implication

Key Points

Cite This Study

2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider