Randomized trial reveals completion lymph-node dissection improves regional control without boosting survival in melanoma sentinel-node metastasis, suggesting routine node removal may be unnecessary.
Immediate completion lymph-node dissection increased the rate of regional disease control and provided prognostic information but did not increase melanoma-specific survival among patients with melanoma and sentinel-node metastases. (Funded by the National Cancer Institute and others; MSLT-II ClinicalTrials.gov number, NCT00297895 .).
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Faries et al. (2017) studied this question.
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