What question did this study set out to answer?

To assess the cost-effectiveness of low-dose computed tomography screening for lung cancer within the National Lung Screening Trial.

November 5, 2014New England Journal of MedicineOpen Access

Cost-Effectiveness of CT Screening in the National Lung Screening Trial

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Authors

WBWilliam C. BlackUniversity of Tennessee at Knoxville IGIlana F. GareenBrown University SSSamir SonejiDuke University

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Implication

Randomized trial finds low-dose CT screening costs $81,000 per QALY gained for lung cancer, indicating cost-effectiveness depends heavily on implementation.

Key Points

To assess the cost-effectiveness of low-dose computed tomography screening for lung cancer within the National Lung Screening Trial.
Analyzed screening data from the randomized National Lung Screening Trial (ClinicalTrials.gov number, NCT00047385).
Calculated the incremental cost per quality-adjusted life year (QALY) gained with low-dose CT screening and evaluated model sensitivity to baseline assumptions.
Screening for lung cancer using low-dose CT was estimated to cost $81,000 per QALY gained.
Modest changes in underlying model assumptions substantially altered the estimated cost-effectiveness ratio, showing that real-world economic value depends on practical implementation.

Cite This Study

Black et al. (2014) studied this question.

synapsesocial.com/papers/69d8d158f39dfae3cad18005 https://doi.org/10.1056/nejmoa1312547

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Implication

Randomized trial finds low-dose CT screening costs $81,000 per QALY gained for lung cancer, indicating cost-effectiveness depends heavily on implementation.

Cost-Effectiveness of CT Screening in the National Lung Screening Trial

Discussion

Member takes

Implication

Key Points

Cite This Study

Cost-Effectiveness of CT Screening in the National Lung Screening Trial

Discussion

Member takes

Implication

Key Points

Cite This Study

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