Corticosteroid nasal irrigations are more effective than simple sprays in a randomized double‐blinded placebo‐controlled trial for chronic rhinosinusitis after sinus surgery

Key Points

• To determine whether corticosteroid delivered via nasal irrigation provides superior efficacy compared to a simple nasal spray in postsurgical chronic rhinosinusitis patients.
• Conducted a randomized, double-blind, placebo-controlled trial.
• Evaluated postsurgical patients presenting with diffuse or patchy chronic rhinosinusitis (CRS).
• Compared topical corticosteroid administration delivered via nasal irrigation versus standard nasal spray.
• Corticosteroid delivery by nasal irrigation was clinically superior to simple nasal spray administration in postsurgical patients.
• Superior therapeutic benefits were specifically demonstrated across diffuse and patchy CRS disease distributions.