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January 1, 2012Natural Product Reports

Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms

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ZZZhaoli ZhouBengbu Medical CollegeYYYaxi YangSecond Affiliated Hospital of Guangzhou Medical UniversityJDJian DingYuxi Normal University

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Zhou et al. (2012) studied this question.

synapsesocial.com/papers/69d8d63e17a1cc0598d18ad2https://doi.org/10.1039/c2np00088a
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tumor inhibitors. LXXIV. Triptolide and tripdiolide, novel antileukemic diterpenoid triepoxides from Tripterygium wilfordii1972 · 511 citations
  2. 2Triptolide modulates T‐cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis2008 · 48 citations
  3. 3Enhanced Antitumor Effect of Combined Triptolide and Ionizing Radiation2007 · 48 citations
  4. 4Synergistic Effect of Triptolide and Tacrolimus on Rat Cardiac Allotransplantation2004 · 14 citations