MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1CCR2 modulates inflammatory and metabolic effects of high-fat feeding2005 · 1,473 citations
2. 2Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -31996 · 321 citations
3. 3Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance2003 · 5,751 citations
4. 4Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid¹1998 · 1,530 citations
5. 5CCR11 Is a Functional Receptor for the Monocyte Chemoattractant Protein Family of Chemokines2000 · 96 citations