Why the study?
Does Pulmonary Arterial Capacitance (PAC) predict long-term prognosis in Advanced Heart Failure?
Does Pulmonary Arterial Capacitance (PAC) predict long-term prognosis in Advanced Heart Failure?
Pulmonary arterial capacitance is strongly related to RV dysfunction, poor long-term prognosis, and response to therapy in advanced heart failure.
Supports PAC for risk stratification in advanced HF; leaves open whether it should guide therapy.
PAC bundles the effects of PVR and left-sided filling pressures on RV afterload, explaining its strong relation with RV dysfunction, poor long-term prognosis, and response to therapy.
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Dupont et al. (2012) studied this question.
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