Prolonged silent carriage, genomic virulence potential and transmission between staff and patients characterize a neonatal intensive care unit (NICU) outbreak of methicillin-resistant Staphylococcus aureus (MRSA)

Sharline Madera; Nicole McNeil; Paula Hayakawa Serpa; Jack Kamm; Christy Pak; Carolyn Caughell; Amy Nichols; David Dynerman; Lucy M. Li; Estella Sanchez-Guerrero; Maíra Phelps; Angela M. Detweiler; Norma Neff; Helen Reyes; Steve Miller; Deborah S. Yokoe; Joseph L. DeRisi; Lynn Ramírez-Àvila; Charles Langelier

doi:10.1017/ice.2022.48

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Abstract

Silent transmission of MRSA between HCP and NICU patients likely contributed to a NICU outbreak involving a virulent MRSA strain. WGS enabled data-driven decision making to inform implementation of infection control policies that mitigated the outbreak. Prospective WGS coupled with epidemiologic analysis can be used to detect transmission events and prompt early implementation of control strategies.

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Madera et al. (2022) studied this question.

synapsesocial.com/papers/69d8f40fade63f05b9bedf5b https://doi.org/10.1017/ice.2022.48

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Prolonged silent carriage, genomic virulence potential and transmission between staff and patients characterize a neonatal intensive care unit (NICU) outbreak of methicillin-resistant Staphylococcus aureus (MRSA)

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Abstract

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Prolonged silent carriage, genomic virulence potential and transmission between staff and patients characterize a neonatal intensive care unit (NICU) outbreak of methicillin-resistant Staphylococcus aureus (MRSA)

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Abstract

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