Why the study?
Does approximately 12% alpha-MyHC expression increase peak normalized power output in rat cardiac myocyte fragments compared to 0% expression?
Population
Rat cardiac myocyte fragments
Comparison
Expression of approximately 12% alpha-MyHC vs Expression of approximately 0% alpha-MyHC
Design
Preclinical
Authors
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Small alpha-MyHC boosts rat myocyte power; leaves open translation to human myocardial performance.
Does approximately 12% alpha-MyHC expression increase peak normalized power output in rat cardiac myocyte fragments compared to 0% expression?
Even small amounts of alpha-MyHC expression (approximately 12%) significantly augment peak normalized power output in cardiac myocytes, highlighting its functional importance in myocardial performance.
Herron et al. (2002) studied this question.
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