Diagnostic concordance and discordance between angiography-based quantitative flow ratio and fractional flow reserve derived from computed tomography in complex coronary artery disease

Hideyuki Kawashima; Norihiro Kogame; Masafumi Ono; Hironori Hara; Kuniaki Takahashi; Johan H. C. Reiber; Brian Thomsen; Robbert J. de Winter; Kaoru Tanaka; Mark La Meir; Johan De Mey; Ulrich Schneider; Torsten Doenst; Ulf Teichgräber; William Wijns; Saima Mushtaq; Giulio Pompilio; Antonio L. Bartorelli; Daniele Andreini; Patrick W. Serruys; Yoshinobu Onuma

doi:10.1016/j.jcct.2022.02.004

Why the study?

Does angiography-based quantitative flow ratio (QFR) correlate with fractional flow reserve derived from computed tomography (FFRCT) in patients with complex CAD?

Structured PICO

Does angiography-based quantitative flow ratio (QFR) correlate with fractional flow reserve derived from computed tomography (FFRCT) in patients with complex CAD?

P

Population

Patients with complex coronary artery disease (CAD)

I

Intervention

Angiography-based quantitative flow ratio (QFR)

C

Comparator

Fractional flow reserve derived from computed tomography (FFRCT)

O

Outcome

Diagnostic concordance and discordance between QFR and FFRCTsurrogate

QFR and FFRCT demonstrate strong diagnostic concordance in patients with complex CAD, particularly for lesions located in the right coronary artery.

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Implication

QFR may offer a CT-independent option in complex CAD; leaves open need for outcome trials before adoption.

Abstract

In patients with complex CAD, QFR and FFRCT were strongly correlated. The location of the lesion in RCA was associated with the highest diagnostic concordance between QFR and FFRCT.

Discussion

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Cite This Study

Kawashima et al. (2022) studied this question.

synapsesocial.com/papers/69d8f972183921ebcaae43e8 https://doi.org/10.1016/j.jcct.2022.02.004

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Diagnostic concordance and discordance between angiography-based quantitative flow ratio and fractional flow reserve derived from computed tomography in complex coronary artery disease

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Diagnostic concordance and discordance between angiography-based quantitative flow ratio and fractional flow reserve derived from computed tomography in complex coronary artery disease

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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