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Unknown mechanisms hinder targeted therapies for isolation-related CVD; leaves open molecular pathways for intervention development.
Elucidation of the molecular mechanisms of how CVD is induced by loneliness and social isolation requires additional studies. Understanding of the pathomechanisms is essential for the development of therapeutic strategies to prevent the detrimental effects of social stress on health. Antioxid. Redox Signal. 28, 837-851.
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Xia et al. (2017) studied this question.
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