Does early combination therapy with statins and ezetimibe reduce cardiovascular outcomes in patients after myocardial infarction compared to delayed combination therapy or statin monotherapy?
Early initiation of ezetimibe combined with statins after myocardial infarction is recommended to prevent avoidable cardiovascular harm associated with delayed combination therapy or statin monotherapy.
MI care pathways should implement early combination therapy with statins and ezetimibe as standard care, because delaying use of combination LLT or using high-intensity statin monotherapy is associated with avoidable harm.
Leósdóttir et al. (Tue,) studied this question.