Why the study?
Heart disease mortality rates continue to rise in young women aged 35 to 54 years, who face higher ischemic heart disease mortality than comparably aged men and similar mortality to older women.
This ACC working group consensus highlights rising ischemic heart disease mortality and underutilization of guideline-directed care in young women aged 35 to 54 years, providing pragmatic management strategies for obstructive CAD, SCAD, MINOCA, and microvascular dysfunction.
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Intensify guideline-directed care in women aged 35-54 to reverse rising IHD mortality; extends prior data with targeted strategies for CAD phenotypes.
The Cardiovascular Disease in Women Committee of the American College of Cardiology convened a working group to develop a consensus regarding the continuing rise of mortality rates in young women aged 35 to 54 years. Heart disease mortality rates in young women continue to increase. Young women have increased mortality secondary to ischemic heart disease (IHD) compared with comparably aged men and similar mortality to that observed among older women. The authors reviewed the published evidence, including observational and mechanistic/translational data, and identified knowledge gaps pertaining to young women. This paper provides clinicians with pragmatic, evidence-based management strategies for young women at risk for IHD. Next-step research opportunities are outlined. This report presents highlights of the working group review and a summary of suggested research directions to advance the IHD field in the next decade.
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Minissian et al. (2022) conducted a review in Ischemic heart disease (IHD).
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