Key result
Rising CAD in young women involves gender-specific risks and atypical presentations that drive underdiagnosis.
Why the study?
Coronary artery disease incidence is increasing in young women, who have gender-specific risk factors, often atypical presentations, and remain underestimated regarding cardiac risk.
Highlights the increasing incidence and underdiagnosis of coronary artery disease in young women, emphasizing the need for awareness of gender-specific risk factors and atypical presentations.
Answers are grounded in this paper and cite their sources.
Raises awareness of underdiagnosis risk in young women; leaves open optimal screening approaches pending dedicated trials.
Cardiovascular diseases (CVD) are the dominant cause of mortality. At the same time, women, especially young ones, often remain objectively underestimated regarding the risk of cardiac diseases. The incidence of comorbidities is currently increasing, including young people. The incidence of coronary artery disease in young women is also increasing (18—44 years). In addition to generally accepted risk factors, this disease in females has gender-specific risk factors (early menarche and early menopause, some gynecological diseases, complicated obstetric history) and is not always characterized by typical clinical course. Atypical clinical presentation and low alertness among medical personnel can lead to underdiagnosis and adverse consequences. In addition, it is now known that many traditional risk factors of cardiac pathology have a greater impact on women for unclear reasons.
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Каретникова et al. (2025) conducted a review in Coronary artery disease. Coronary artery disease in young women (18-44 years) is increasing and characterized by gender-specific risk factors and atypical clinical presentations that can lead to underdiagnosis.
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