Answers are grounded in this paper and cite their sources.
PORCN mutations can be found in all classically affected cases of Goltz-Gorlin syndrome, including males. Somatic and germline mosaicism occur. There is no evident genotype-phenotype correlation.
No takes yet. Share an insight, caveat, or question.
Maas et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: