Molecular characterisation and epidemiology of enterovirus-associated aseptic meningitis in the Western and Eastern Cape Provinces, South Africa 2018–2019

Nokwazi Nkosi; Wolfgang Preiser; Gert U. van Zyl; Mathilda Claassen; Nadine Cronjé; Jean Maritz; Howard Newman; Kerrigan McCarthy; Genevie Ntshoe; Vivien Essel; Stephen N.J. Korsman; Diana Hardie; Heidi Smuts

doi:10.1016/j.jcv.2021.104845

April 24, 2021Journal of Clinical VirologyOpen Access

Molecular characterisation and epidemiology of enterovirus-associated aseptic meningitis in the Western and Eastern Cape Provinces, South Africa 2018–2019

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Structured PICO

P

Population

Patients with enterovirus-associated aseptic meningitis in the Western and Eastern Cape Provinces, South Africa

I

Intervention

Molecular typing using stool samples

O

Outcome

Molecular characterisation and epidemiology of the outbreak

Stool samples are valuable for molecular typing of enterovirus in patients with CSF-confirmed aseptic meningitis.

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Implication

Stool sampling may aid EV typing in aseptic meningitis outbreaks; hypothesis-generating and requires prospective validation before changing practice.

Abstract

The aseptic meningitis outbreak was associated with echovirus 4. Stool samples are valuable for molecular typing in CSF confirmed EV-associated aseptic meningitis.

Discussion

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Nkosi et al. (2021) studied this question.

synapsesocial.com/papers/69d90834542abee8b0d17d1e https://doi.org/10.1016/j.jcv.2021.104845

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Molecular characterisation and epidemiology of enterovirus-associated aseptic meningitis in the Western and Eastern Cape Provinces, South Africa 2018–2019

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Molecular characterisation and epidemiology of enterovirus-associated aseptic meningitis in the Western and Eastern Cape Provinces, South Africa 2018–2019

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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