Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy

Jumin Huang; Di Liu; Yuwei Wang; Liang Liu; Jian Li; Jing Yuan; Zhi‐Hong Jiang; Zebo Jiang; W.L. Wendy Hsiao; Haizhou Liu; Imran Khan; Ying Xie; Jian‐Lin Wu; Ya‐Jia Xie; Yizhong Zhang; Yu Fu; Junyi Liao; Wenjun Wang; Huanling Lai; Axi Shi; Jun Cai; Lianxiang Luo; Runze Li; Xiaojun Yao; Xing‐Xing Fan; Qibiao Wu; Zhongqiu Liu; Peiyu Yan; Jing‐Guang Lu; Ming-Rong Yang; Lin Wang; Yabing Cao; Hong Wei; Elaine Lai‐Han Leung

doi:10.1136/gutjnl-2020-321031

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Abstract

Our results demonstrate that GPs combined with αPD-1 mAb may be a new strategy to sensitise non-small cell lung cancer patients to anti-PD-1 immunotherapy. The gut microbiota can be used as a novel biomarker to predict the response to anti-PD-1 immunotherapy.

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Huang et al. (2021) studied this question.

synapsesocial.com/papers/69d9094531221da40c64f4ed https://doi.org/10.1136/gutjnl-2020-321031

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Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy

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Abstract

Discussion

Cite This Study

Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy

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Abstract

Discussion

Cite This Study

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