Why the study?
Does prophylactic phenylephrine reduce hypotension in women undergoing caesarean section under spinal anaesthesia?
Population
21 RCTs pooling 1504 women undergoing caesarean section under spinal anaesthesia
Comparison
Prophylactic phenylephrine infusion vs Placebo, ephedrine infusion, or ephedrine…
Design
Meta-analysis
Authors
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Supports prophylactic phenylephrine to prevent hypotension in spinal caesarean anesthesia; confirms benefit versus placebo in Level 1 evidence.
Does prophylactic phenylephrine reduce hypotension in women undergoing caesarean section under spinal anaesthesia?
Prophylactic phenylephrine significantly reduces the risk of hypotension and nausea/vomiting during caesarean section under spinal anaesthesia compared to placebo or ephedrine.
Heesen et al. (2013) studied this question.
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