What is the residual stroke or systemic embolism risk in patients with atrial fibrillation prescribed oral anticoagulants?
Despite oral anticoagulation, high-risk patients with atrial fibrillation maintain a clinically significant residual stroke/SE risk of 1.5% to 2.5% per year, highlighting the need for additional prevention strategies.
AF type, CHA2DS2-VASc score, and stroke history can identify patients with AF, who despite oral anticoagulation have a residual stroke/SE risk of 1.5% to 2.5% per year. Evaluation of additional stroke/SE prevention strategies in high-risk patients is warranted.
Johnson et al. (Tue,) studied this question.