Why the study?
Do high lipoprotein(a) levels and the rs10455872 variant increase the risk of incident aortic valve stenosis?
Do high lipoprotein(a) levels and the rs10455872 variant increase the risk of incident aortic valve stenosis?
High lipoprotein(a) levels and the rs10455872 genetic variant are associated with an increased risk of incident aortic valve stenosis, suggesting a potential causal relationship.
Patients with high lipoprotein(a) levels are at increased risk for AVS. The rs10455872 variant, which is associated with higher lipoprotein(a) levels, is also associated with increased risk of AVS, suggesting that this association may be causal.
No takes yet. Share an insight, caveat, or question.
Arsenault et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: