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December 1, 2015Particle and Fibre ToxicologyOpen Access

Lung carcinogenicity of inhaled multi-walled carbon nanotube in rats

Tatsuya Kasai Yumi Umeda Makoto Ohnishi Takashi Mine Hitomi Kondo Tetsuya Takeuchi Michiharu Matsumoto Shoji Fukushima

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Key Points

To determine the carcinogenic potential of inhaled multi-walled carbon nanotubes (MWNT-7) in the respiratory system of rats.
Evaluated male and female F344 rats exposed to inhaled multi-walled carbon nanotubes (MWNT-7).
Demonstrated clear evidence of lung carcinogenicity in both male and female F344 rats following MWNT-7 inhalation.
Produced no observable cases of pleural mesothelioma in either sex.

Implication

Animal inhalation study reveals lung carcinogenicity from MWNT-7 in male and female rats, indicating pulmonary cancer hazards without pleural mesothelioma.

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Cite This Study

Kasai et al. (2015) studied this question.

synapsesocial.com/papers/69d91ac29402b8412aa3c1c2 https://doi.org/10.1186/s12989-016-0164-2

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