Burden, Clinical Characteristics, Risk Factors, and Seasonality of Adenovirus 40/41 Diarrhea in Children in Eight Low-Resource Settings

Figures

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  Figure 1.. Attributable incidence of adenovirus 40/41 diarrhea in children 0–24 months of age in the MAL-ED birth cohort study, estimated by EIA and qPCR (A) and by qPCR for 3-month age groups (B). Abbreviations: EIA, enzyme immunoassay; MAL-ED, Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development Project; qPCR, quantitative polymerase chain reaction.

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  Figure 2.. Annual incidence of adenovirus 40/41 infection by calendar month, monthly average temperature, and rainfall for each site. The solid line represents the predicted incidence, the gray bars represent monthly rainfall, and the dotted line represents temperature.

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  Figure 3.. Incidence of adenovirus 40/41 infection over the course of the study by site and study month. The dotted line represents the predicted incidence of adenovirus 40/41 infection if the cohort age was held constant at 365 days. Week 0 starts on November 10, 2009, and week 230 starts on March 5, 2014.