Global impact of rotavirus vaccine introduction on rotavirus hospitalisations among children under 5 years of age, 2008–16: findings from the Global Rotavirus Surveillance Network

Figures

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  Figure 1:. Countries participating in the GRSN The map shows all countries that participated in 2016 and those that only participated during any of the years 2008–15, separately. Not applicable refers to disputed areas. GRSN=Global Rotavirus Surveillance Network.

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  Figure 2:. Data selection for analysis of global impact of rotavirus vaccine on acute gastroenteritis hospitalisations among children younger than 5 years of age enrolled in the GRSN, 2008–16 Sites could be excluded for more than one reason. GRSN=Global Rotavirus Surveillance Network.

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  Figure 3:. Rotavirus positivity in countries without rotavirus vaccine, 2008–16 Pre-vaccine data from countries that have introduced rotavirus vaccines as well as data from countries that have not yet introduced rotavirus vaccines. Data are from all sites in countries meeting inclusion criteria and reporting to the Global Rotavirus Surveillance Network. Boxplots depict median, 25th, and 75th percentile values. Whiskers denote variability beyond these upper and lower quartiles, with individual dots representing outliers.

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  Figure 4:. Rotavirus positivity in countries with rotavirus vaccine, 2008–16 Post-vaccine data are shown from countries that have introduced rotavirus vaccine. Year is calculated in reference to vaccine introduction year (year 0). Data are from all sites in countries meeting inclusion criteria and reporting to the Global Rotavirus Surveillance Network. Boxplots depict median, 25th, and 75th percentile values. Whiskers denote variability beyond these upper and lower quartiles, with individual dots representing outliers.

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  Figure 5:. Rotavirus positivity in countries with rotavirus vaccine, by region, 2008–16 Year is calculated in reference to vaccine introduction year (year 0). Data are from sites in countries reporting to the Global Rotavirus Surveillance Network. Boxplots depict median, 25th, and 75th percentile values. Whiskers denote variability beyond these upper and lower quartiles, with individual dots representing outliers. *Two datapoints for pre-vaccine years −5 and −6 were removed from the figure for the European region given only one site contributed for each of these years.

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  Figure 6:. Age distribution of children positive for rotavirus in countries with and without rotavirus vaccine introduction reporting to the Global Rotavirus Surveillance Network, 2008–16 Countries with rotavirus vaccine comprise cases of rotavirus gastroenteritis from all countries that have introduced a rotavirus vaccine. Countries without rotavirus vaccine comprise cases of rotavirus gastroenteritis from countries that have not introduced a rotavirus vaccine and cases that occurred before introduction of the vaccine in those countries that have introduced a vaccine.