Patients with excessive preoperative alignment (>8° of varus or >11° of valgus) have a greater risk of failure (2.3%). Neutral postoperative alignment (2.5° through 7.4° of valgus) improves (1.9% for preoperatively deformed knees) but does not completely eliminate the risk of failure (0.5% for knees that were neutral both preoperatively and postoperatively). Careful attention should be paid to knee alignment during total knee arthroplasty, especially for patients with severe preoperative deformities.
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Ritter et al. (2013) studied this question.
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