Primary Cardiac Diffuse Large B-cell Lymphoma Promptly and Safely Diagnosed with Pericardial Effusion Cytology

Figures

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  Figure 1.. A) An electrocardiogram on admission showed atrial fibrillation and a low voltage. B) Chest radiography revealed moderate cardiomegaly and bilateral pleural effusion.

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  Figure 2.. Cardiac echocardiography showed massive pericardial effusion (yellow arrowhead). An abnormal mass was situated on the free wall of the right atrium and ventricle (green arrowhead), part of which was adjacent to the tricuspid valve and had mobility in the intracardiac space (red arrowhead). (LA: left atrium, RA: right atrium, RV: right ventricle)

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  Figure 3.. A) Cytology revealed highly pleomorphic large lymphocytes with markedly irregular nuclei on Hematoxylin and Eosin staining (×400). B) Immunostaining showed that the neoplastic lymphoid cells were diffusely positive for CD20 (×400).

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  Figure 4.. A, C) Contrast-enhanced computed tomography revealed an abnormal mass situated on the free wall of the right atrium and ventricle (yellow arrowhead). B, D) After six cycles of chemotherapy, the tumor showed a marked reduction in size.

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  Figure 5.. A, B, C, D) An abnormally high accumulation of FDG was detected in the cardiac tumor (SUVmax 29.33). E, F, G, H) The abnormal uptake decreased after six cycles of chemotherapy.