June 24, 2019Open Access

METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma

TLTing LiNanjing Medical University PHPei-Shan HuSun Yat-sen University ZZZhixiang ZuoSun Yat-sen University

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Abstract

Overall, our study revealed that METTL3, acting as an oncogene, maintained SOX2 expression through an m6A-IGF2BP2-dependent mechanism in CRC cells, and indicated a potential biomarker panel for prognostic prediction in CRC.

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Li et al. (Mon,) studied this question.

synapsesocial.com/papers/69d945499402b8412aa3cc10 https://doi.org/https://doi.org/10.1186/s12943-019-1038-7

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