Serious adverse respiratory events are very rare in pediatric procedural sedation in the ED, providing quantitative risk estimates to facilitate informed consent and shared decision-making.
Research meaning:* Extends safety data for procedural sedation or confirms the safety profile.
Serious adverse respiratory events are very rare in paediatric procedural sedation in the ED. Emesis and agitation are the most frequent adverse events. Hypoxia, a late indicator of respiratory depression, occurs in 1.5% of sedations. Laryngospasm, though rare, happens most frequently with ketamine. The results of this study provide quantitative risk estimates to facilitate shared decision-making, risk communication, informed consent and resource allocation in children undergoing procedural sedation in the ED.
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Bellolio et al. (2016) studied this question.
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